Rosacea News December 2007

1. Senetek Trialling Pyratine 6 / PRK124

December 30th, 2007, by Digital Davo | clinical trials, papules & pustules

A new trial has just been posted that will be looking at how Pyratine 6 (a variant of Kinetin) treats the papules & pustules, redness and visible blood vessels of rosacea. From Clinical Trial NCT00580723: Effects of PRK 124 Lotion in Acne Rosacea The purpose of this open-label study is to determine the tolerance and efficacy of twice-daily application …

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2. Nerve Growth Factor inhibitor – acerola seed extract

December 27th, 2007, by Digital Davo | patents, seborrheic dermatitis

Trawling patent applications is challenging but also interesting. There is a huge mine of information available for us to scavenge information that might lead to future treatments. I thought this patent was interesting because it deals with something that I hadn’t heard of before, but seems like it might have some potential. This patent application makes me wonder if we will see anything else …

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3. acne lotion good for cleaning pen from toys

December 21st, 2007, by Digital Davo | acne treatments, in the news

OK a semi-serious post for this time of year. An interesting blog posting over at Baby Toolkit suggests that 10% benzyl peroxide cream and sunlight is perfect for removing pen marks from a plastic doll. From Clear Unsightly Blemishes: the Case of the Ballpoint Baby Doll Here is before ;   and here is after …

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4. Patents abound for treating rosacea with alpha agonists

December 19th, 2007, by Ben | patents

Their has been much talk lately about using alpha adrenoceptor agonists as rosacea treatments because they show vasoconstrictor actions. Some examples are brimonidine, oxymetazoline, naphazoline, and others.

There are quite a few patents out there discussing these, and even testing some of them. Some of these patents have been mentioned before on the site.

Here are links to some of these patents.

US20040242588
Compounds, …

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5. kinetin & niacinamide for anti-aging

December 14th, 2007, by Digital Davo | moisturizers, topicals 

This study shows that kinetin and niacinamide work together well to provide anti-aging effects for asian skin. Previous studies that have been highlighted by Rosacea News have also shown that topical kinetin is a good anti-aging moisturizer for rosacea sufferers and may even show some benefit for rosacea symptoms. The clinical anti-aging effects of topical kinetin …

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6. get ready for ocular oracea

December 12th, 2007, by Digital Davo | doxycycline, ocular rosacea, oracea

Thanks for the tip from Ben. A clinical trial listed for treating both facial and ocular rosacea with Oracea suggests that Oracea might soon be marketed directly as an ocular rosacea treatment. This phase 2 trial’s purpose is to determine the safety and efficacy of sub-antimicrobial dose doxycycline in the treatment of patients who have both blepharitis and facial rosacea. The trial …

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7. FDA approves Lyrica for Fibromyalgia

December 10th, 2007, by Digital Davo | in the news

Whilst this was announced back in June this year, I thought it was worthwhile highlighting it here in case it is of interest to rosacea sufferers who also suffer from chronic pain. From the FDA Consumer Update: Living with Fibromyalgia, First Drug Approved People with fibromyalgia have typically turned to pain medicines, antidepressants, muscle relaxants, and sleep medicines. On …

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8. how Collagenex are Promoting Oracea

December 6th, 2007, by Digital Davo | oracea, tetracyclines

A recent investor presentation from Collagenex shows some interesting insights into how Collagenex are promoting Oracea. Oracea is promoted as safe and effective for long term use. It was reported that the average duration of Oracea therapy is 4 months, compared to an average of 2.5 months for other rosacea prescriptions. 52% of Oracea prescriptions are refills – the presentation suggests that …

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9. treating ocular rosacea with amniotic membrane transplant

December 4th, 2007, by Digital Davo | ocular rosacea

This case report of one patient shows a remarkable treatment possibility for severe ocular rosacea. The patient also suffered from papulopustular rosacea and rhinophyma and did not respond to full dose doxycycline. Three attempts to glue his perforated cornea failed. The paper suggests that corneal perforation is quite rare in ocular rosacea.

The amniotic membrane transplant was a success, both sealing the perforation, and restoring good …

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10. genetic links for psoriasis, lupus

December 3rd, 2007, by Digital Davo | research

A quick news bite about some new links found for a genetic root for psoriasis and lupus. I like that the reporter doesn’t try to dress up this announcement as anything other than a small advance in our knowledge of these 2 diseases. The research into a provable genetic link for rosacea symptoms is still at a very early stage. Maybe one day …

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