Rosacea News October 2009

Rosacea News October 2009

1. Oracea wins award for cute marketing

I can’t say that I know how much industry weight is carried by the publication Medical Marketing & Media, but they have awarded Galderma the Gold Award for `Best Individual Product Advertisement in Consumer Press’ for their …

2. Cetaphil adds UVA/UVB Defense SPF 50

Galderma announced in February a new SPF 50 Facial Sunscreen called Cetaphil UVA/UVB Defense SPF 50. Actually Galderma is not promoting this product as a sunscreen, but as a facial moisturizer. Said to be non-greasy and ..

3. Claim your Rosacea Community Blog Now !

Always wanted to have a blog or little corner of the internet you could call your own ? Well now you can. Every registered member of the Rosacea Support Community can have their very own blog area.

So please feel free to start your own Rosacea Community Blog.
Why would I want one of those ?
Your own blog will allow you post your thoughts, ideas, ..

4. IPL good for dry eyes too

WSOC-TV Charlotte, Carolina is syndicating a story about using IPL to successfully treat dry eye. Dr. Coad details how he is using IPL to treat this eye condition that is sometimes also found in ocular rosacea sufferers. Dr. Mannis in his interview for the RSRP had this to say about IPL and ocular rosacea. Q: Do you think ..

5. Topical Oxygen being trialled for sun damaged skin

A trial seeking participants interested in being treated with topically disolved oxygen (TDO) has been posted to clinicaltrials.gov. Aria Aesthetics is listed as supplying the `Aria Regimens’ in 0.5%, and 0.25%. As the trial is double blind and placebo controlled, a third group will receive no TDO during their treatments. Zoe Draelos MD is listed as a contact for the trial. Dr. Draelos ..

6. Clarisonic now available in the UK

The Daily Mail has published an article reviewing the Clarisonic in their Femail Beauty section. This article is no doubt motivated by the Clarisonic recently being launched in the UK (available exclusively via Space NK). The `oversized electric toothbrush’ is ..

7. Sansrosa starts strength tests, approaches final hurdle

In an encouraging sign that Sansrosa is slowly but surely progressing towards FDA approval, the clinicaltrials.gov register lists Galderma recruiting for a dose-finding trial for a product code named CD07805/47. The aim of this trial is show which strength is the most suitable for general use. Trial participants will be using one of 4 different strengths: 0.07%, 0.18%, %0.50 or effectively %0 contained ..

8. NRS research results explained

The NRS has just posted an easy-to-read summary of recent NRS funded research results. The update mentions the `Gallo Research’ and describes it ; “Dr. Richard Gallo at the University of California-San Diego found a consistently aberrant innate immune response in individuals with rosacea to environmental and emotional triggers.” Spin-off research related to type I interferon, plasmacytoid dendritic cells and enzyme involvement ..

9. Tetracyclines and Rosacea: what we already knew

Reading this just published abstract highlights for me just how slowly indeed research moves along. These recently proposed methods of action of tetracyclines seem to embody far from ground breaking research. We learnt in 2007 that tetracyclines have anti-inflammatory actions:  “Tetracyclines are known to exhibit multiple significant anti-inflammatory actions … the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation.

Rosacea News August/September 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release. Promiseb (probably pronounced Promi-seb) is launching in the U.S. via Promius Pharma, after being licensed from Sinclair Pharma in 2007….

Rosacea News September 2009

1. Oracea worth $104m a year, good news for Sansrosa

According to a press release via Reuters, sales of Oracea were approximately $104 million for the twelve-month period ending July 2009. This figure is up almost 200% from the previously reported sales of $52.5 million in …

2. Impax Laboratories joins the generic Oracea battle

September 21st, 2009, by Digital Davo | oracea, patents | Edit

In a further confirmation that the low dose doxycycline market is a becoming a fighting ground, a recent press release states that Impax Laboratories has filed “Abbreviated New Drug Application ("ANDA") containing a paragraph IV certification for a generic version of ORACEA with the U.S. Food & Drug Administration ("FDA").” This is a challenge to the patents held by Galderma, relating …

3. PSF reduces the pain of Pulsed Dye Laser

This just published abstract from Lasers in Medical Science, shows that the extreme pain associated with pulsed dye laser, when used to treat port wine stains, can be relieved by using Pneumatic Skin Flattening (PSF). Pneumatic Skin Flattening uses a vacuum to compress the skin underneath the area being treated. Blood is eliminated from the treatment area. The technique is said …

4. FDA gets tough with Aczone

The FDA has issued a warning letter to Allergan, the makers of Aczone for overstating the efficacy of Aczone and also for understating the possible side effects. In a sign that the FDA is watching carefully the claims that vendors use when advertising their products, the warning letter calls out a journal advertisement for Aczone as violating the Federal Food, Drug, and Cosmetic Act. …

Rosacea News August 2009

Rosacea News August 2009

1. water soluble sunscreen anyone ?

An interesting looking patent application proposing a water based sunscreen for rosacea sufferers has surfaced at the USPTO. Many rosacea sufferers will know the trauma of finding a sunscreen that is gentle enough to not cause a bad reaction and effective enough to protect from the harm of the sun. For me the sun has always been my worst trigger. Certainly physical sunscreens …

2. so does acupuncture work, or not ?

For me acupuncture has always been part of some kind of ancient mythology. Humans are controlled by a brain that has complex neurological pathways to all corners of their bodies. Can inserting fine needles in to the so-called meridians along energy …

3. Epsom salts or Milk of Magnesia actually works ?

A few newspapers have picked up this Question & Answer article where rosacea sufferers are encouraged to try Epsom salts (magnesium sulfate) or Milk of Magnesia on their skin.

One can imagine that a bath with Epsom salts would be relaxing, but …

4. Sebclair launches as Promiseb Cream

I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release.

Rosacea News July 2009

Rosacea News July 2009

1. Doxium being trialled as Pulsed Dye Laser adjunct

A new trial is recruiting participants to evaluate the use of calcium dobelisate as a combination therapy, along with Pulse Dye Laser to treat the erythema, flushing and telangectasia associated with erythematotelangietatic rosacea. We know from rosacea and doxium that “Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity.” Clinical Trial …

2. Calling all Rosacea Researchers: get your grants now !

The National Rosacea Society is calling for grant applications for their 2010 allocation. Good to see that they want an emphasis on research into the cause rosacea. From New Grants Available Monday, July 27, 2009 New grants are available from the National Rosacea Society (NRS) to support research on potential causes and other …

3. Abstracts: Elidel, Bacteria & Ocular prevalence

The following abstracts don’t deserve a Rosacea News item on their own, but are interesting enough to give a mention here in this Abstract Roundup. Elidel no better than Metrogel for lumps and bumps of rosacea. A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea: a randomized open-label clinical trial. Clin Exp Dermatol. 2009 …

4. Sol-Gel Trialling Benzoyl Peroxide (DER 45 EV) for Rosacea ?

An intriguing Clinical Trial has been listed on the ClinicalTrials.gov web site. The product know only as DER 45 EV Gel (in strengths of 1% and 5%) has been listed in a dose-range trial for the papules and pustules of rosacea. Clinical Trial NCT00940992, A Dose-Range of DER 45-EV in Treatment of Rosacea (SGT-EBPO1-09) …

5. we’ve all been exposed to demodex bacteria proteins ?

An article published today in the Irish Times takes one more step in the direction of showing an association between demodex mites and rosacea. Readers of Rosacea News will know that a lot of research has tried to find a causative link between the presence of demodex mites and rosacea symptoms. Some progress towards a link between the two was …

6. acupuncture, yoga, hat and moisturiser says Daily Mail

We are seeing more and more newspaper health and beauty articles that relate to rosacea. Today the UK’s MailOnline has an intriguingly titled article – How waggling my feet has helped my red face. To save you …

7. accutane and drinking alcohol – no problem, apparently

This just published abstract is suggesting that it appears to be safe to consume alcohol while taking accutane. Whilst the Accutane Prescribing Information does not prohibit the consumption of alcohol, it does suggest that alcohol …

8. CeraVe Hydrating Cleanser and CeraVe Moisturizing Lotion User Reviews

Recently the manufacturers of Finacea, Intendis, and Coria Laboratories, have begun promoting a new combination package it is calling Finacea plus. This package encourages rosacea sufferers to combine a tube of Finacea with CeraVe Hydrating …

9. Restasis (cyclosporine) as ocular rosacea treatment

It is good to see more published research backing topical cyclosporine (Restasis, Allergan) as a treatment for ocular rosacea. Restasis (cyclosporine ophthalmic emulsion 0.05%) has been shown to increase tear production and improve the quality of naturally produced tears and is …

Rosadyn Vasculokinetic and Skin Health Support

The Rosadyn site is full of scientific terminology.

Addresses all symptoms of Rosacea: Facial Redness and flushing skin inflammation and sensitivity inflammatory bumps and breakouts.

Advanced non-prescription oral nutraceutical for vascular, ocular and skin support

Targets the root precursors of facial redness, inflammation and flushing.

Developed by Dr. Geoffrey Nase PhD., Rosacea Specialist and Researcher.

Further claims about Rosadyn: advanced pharmaceutical-grade nutraceutical, vasculokinetic, Absorption Enhancement Blend, Hypothalamus Support, Hypothalamic overdrive.

Rosacea News June 2009

Rosacea News June 2009

1. doryx + applesauce, for those who can’t swallow tablets

If you have trouble swallowing tablets, here is an official FDA sanctioned tip. Open the tablet and sprinkle the delayed release pellets on to a spoonful of applesauce. This is a good option for anyone who finds swallowing the …

2. NYTimes says no natural remedies for rosacea

The New York Times has an article today keenly titled Natural Remedies for Rosacea?. The question is one that many rosacea sufferer seek answered – are there any effective treatments for rosacea that don’t include the use of antibiotics or prescription potions and lotions ? The answer comes from one of the premier rosacea experts – Dr. Frank C. Powell. Here is an extract …

3. Favourite Over The Counter treatments

Do you have a favourite over the counter treatment for your rosacea ? Depending on your health insurance and access to doctors and pharmacies, prescription treatments are out of the reach of many rosacea sufferers. So what can you try as a rosacea treatment that is easy to source, cheap and …

4. Vita-Oil Release Next Week. Tinted ZincO in July

Here is an announcement from RosaceaCare: “Earlier this year, we announced that four important and popular rosacea products that had been unavailable for many months would thereafter, by special arrangement with the originator, be manufactured and distributed by the Rosacea Care Company. We are pleased to tell you that the first of these, the much-loved Vita-Oil, will be released and ready to ship this …

5. Is Oracea different to 50mg doxycycline ?

I came across the following graph in a recent presentation at the recent AAD meeting and figured it was interesting enough to highlight it here. The following graph, sourced from Collagenex (who sell Oracea), shows the blood plasma concentration of doxycycline after taking Oracea compared to 50mg once a day of generic doxycycline. The horizontal axis stretches out to 24 hours post dosage. …

6. Doxium (calcium dobesilate) trialists wanted

Thanks to a comment from Sophie on the post rosacea and doxium (calcium dobesilate) we know that Dr. Cuevas who is responsible for several papers on Dobesilate, is accepting people to try it as a treatment for rosacea. Thanks for the info Sophie.

7. Green Tea helps after IPL

This just published paper is suggesting that the topical application of polyphenol antioxidants (aka green tea) post IPL treatment resulted in more hydrated skin and reduced oxidative degradation of skin lipids. The authors suggest that this will enhance the effects of the IPL therapy.

Common Rosacea Mis spellings

One of the things about rosacea is that it is, well kinda spelled weird like. You can easily misspell it – especially if you hear it said, your chance of writing it correctly are pretty low.

So here we go – the most popular mis-spellings of rosacea, according to the google keywords tool ;

• rosacia
• rosecea
• roscea
• roseacea
• rosasea

I’m sure you’ll see some more in your travels too.

Rosacea News May 2009

Rosacea News May 2009

1. Dermatology Times highlights Afrin and Sansrosa

The Dermatology Times is running an article highlighting the novel and unlikely rosacea treatments based on a nasal decongestant and a glaucoma treatment. They of course are referring to Oxymetazoline and Brimonidine. The article mentions the positive results from the “most recent research” on Brimonidine ; In the most recent research, a double-blind study for Galderma, a 1 g application …

2. Ocular rosacea: oligosaccharide based treatments

An interesting looking patent that was filed in 2006 has come up as reaching filed status. This patent covers the relationship between an oligosaccharide specific to an inflammatory disease, more specifically ocular rosacea. The discovery may lead to both a definitive diagnostic test and new treatments for ocular rosacea. One of inventors of this patent is well known to rosacea sufferers. Dr. Mark Mannis …

3. Oracea too expensive ?

Some interesting comments from KUNC commentator Dr. Marc Ringel via a NPR segment. He raises two points that are worth discussing. Firstly is Oracea really any better than generic doxycycline and secondly what does it say about the pharmaceutical industry (and insurance companies – ed) that a repackaged old product  can be so expensive ? Galderma would say that Oracea is sub-antimicrobial …

4. would you like an electric current with your topical ?

A couple of recently awarded patents look both interesting and slightly scary for potential rosacea treatments. These patents cover some kind of device that is stuck to the skin. A small electric charge is used to help an active chemical cross the skin barrier. Some kind of carrier (an electrolyte) allows Zinc ions to flow between the electrodes, across the skin, creating a small charge. …

5. LED post laser helps recover from redness

A recent abstract from Dermatologic Surgery suggests that treatment with 590nm LED therapy following fractional laser skin resurfacing helps patients more quickly recover from the post treatment erythema. Whilst skin resurfacing with a laser is considered dangerous for rosacea sufferers, the fact that LED therapy help speed up recovery is good news for LED and low level light therapy in general. The study showed that …

6. novel tetracycline from Warner Chilcott and Paratek

Some very preliminary internet crumbs about a new possible rosacea treatment under development. The treatment under development is listed as a “novel tetracycline”. Warner Chilcott Limited calls itself a “specialty pharmaceutical company, that engages in the development, manufacture, marketing, and sale of branded prescription pharmaceutical products in women’s healthcare and dermatology segments primarily in the United States”. In the WCRX 2007 Annual …

7. Botox for neural symptoms and flushing, user reviews

Some interesting discussions from both experts and users of botox treatments for rosacea have are emerging online and are worth reviewing. A quick search on Google shows that several clinics are now offering botox as part of their rosacea treatments. Better known for it’s cosmetic use, the highly toxic protein known …

8. Glyco Mira developing anti-cathelicidin treatment ?

A brief paragraph in a recent article in The Salt Lake Tribune looks quite interesting. A company called Glyco Mira (seemingly a company without a web site) is developing a drug that “may be able to cure the underlying problem that causes rosacea”. A pretty tall prediction for sure. So what are they talking about ? Glyco Mira have licensed and anti-inflammatory drug from the …

Rosacea News April 2009

Rosacea News April 2009

1. Pyratine XR launches, user reviews

fact sheets, in the news, kinerase, moisturizers, topicals, user reviews

Showing just how important the internet is becoming for marketing new cosmetics, Pyratine XR has recently launched with a lot of press activity. As well as Senetek’s press releases on the internet I was also contacted by 2 …

2. Video Tips from Rosacea Rescue Squad

in the news

The Galderma rosacea promotional site Best Face Forward has a new section titled Rosacea Rescue Squad. The site features some video tips from Dr. Hilary Baldwin and Charla Krupp. Dr. Baldwin, who is a dermatologist from …

3. moisturize before or after finacea – it doesn’t matter

finacea, moisturizers, topicals

Well here you are, one of the frequently asked questions about rosacea topicals has been answered. Does it matter whether I apply my rosacea prescription topical before or after I use a moisturizer ? This recently available abstract suggests that in fact it doesn’t matter. The study looked at the absorption of finacea before and after moisturizer lotions were applied and was unable …

4. GlaxoSmithKline to buy Stiefel (Rosac/Rosasol)

in the news, topicals

Continuing recent consolidations in the pharmaceutical industry is the report that the giant GlaxoSmithKline (or GSK) are to purchase Stiefel. Stiefel is the manufacturer of …

5. AAD: oxymetazoline, dapsone and light therapy

in the news

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at how Dr. Downie mentions the new and future possible treatments for rosacea. This is encouraging, to see dermatologists discussing what is new and potentially interesting in the field of rosacea. SYM S048, Treatment …

6. AAD: off-label and future rosacea treatments

in the news

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at a couple of slides from Dr. Thiboutot.

Rosacea News March 2009

Rosacea News March 2009

1. ZENMED User Reviews

Those who have been around on the internet for a while won’t have failed to notice ZENMED. ZENMED (they use all capitals) are good at advertising and have a high profile through their advertising campaigns. In fact because Zenmed use Google Adwords you can sometimes see advertisements for them here on rosacea-support.org. When you have a company that you don’t know much about, but has …

2. AAD: natural ingredients have a role in rosacea therapy

As promised in my 67th AAD Meeting SFO, rosacea highlights news item, here are some updates from the conference proceedings and handouts. In this update we’ll look at how Dr. Downie suggests that natural ingredients do have a role in the treatment of rosacea. It is encouraging to see these complementary ingredients feverfew, green tea and licorice getting some mainstream …

3. IPL pain and no gain: Telegraph Health & Well Being

The UK newspaper The Daily Telegraph has a short fluff piece on IPL. As is usually the case with this style of article there is little substance. The reporter was not impressed with the results but was impressed with the pain and bruising and swelling. Intense Pulsed Light (IPL): miracle cure or waste of money? It is …

4. Galderma suing Mylan Pharmaceuticals over Oracea

Galderma, the makers of Oracea are suing Mylan Pharmaceuticals for allegedly infringing 4 patents related to their sub-antimicrobiotic dose doxycycline product Oracea. State University of New York, Galderma Sue Mylan March 20 (Bloomberg) — The State University of New York, Galderma Laboratories LP and New York University sued generic- drug maker Mylan Pharmaceuticals Inc. for allegedly …

5. Sun linked to rosacea, but which came first ?

The NRS have an entry up on their weblog discussing the link between sunburn and rosacea. A study of 65 healthy subjects and 65 moderate to severe rosacea sufferers found that the rosacea patients `had significantly higher rates of blistering sunburns that those without rosacea’. Sadly there was no conclusion as to whether the extra incidence of sunburn contributed to the severity of …

6. Sansrosa composition revealed in patent application

A new sansrosa patent application has appeared, and from it was can see clearly what formula will be used for the sansrosa gel and sansrosa cream formulations. We don’t know the official name for the product yet, but it seems to make sense to me to call the product Sansrosa Gel and Sansrosa Cream.

Those following the development of sansrosa closely will be encouraged by this …

7. Rosacea Expert Series: IPL & Laser

Continuing our Rosacea Expert series, the Rosacea Support Resource Pages now has a summary of the ongoing Ask a Doctor IPL & Laser sub-forum. Have a read of Laser & IPL: Dr. Peter Crouch, MB.BS, Dr Steve Johnson, MD, Dr. Nicholas Soldo, MD to find out more about the following questions; ACCUTANE WITH RED LIGHT …

8. ho hum: finacea + oracea vs. metrogel 1% + oracea

The Clinical Trials register has listed a new trial for papulopustular rosacea. The trial, sponsored by Intendis, the manufacturer of Finacea, wants to compare the combination of Oracea and Finacea, with the combination of Oracea and Metrogel 1%. It seems clear from this that Intendis would like to position Finacea as a viable alternative to Metrogel. This makes good sense …

9. 67th AAD Meeting SFO, rosacea highlights

The 67th Annual Meeting of the American Academy of Dermatology is due to meet this week in San Francisco. I have to say that the AM09 Program looks a little uninteresting for those following rosacea developments. The program contains a few advertisements from Finacea, the new Instant Relief Mineral Powder from the Clinique Redness solutions range and also Aczone …